| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 101301 | 100 ug | $60 | ||
| 101302 | 500 ug | $180 |
| Clone | 020AR1 |
|---|---|
| Application | FC |
| Reactivity | Human |
| Format | Purified |
| Target Name | CD20, MS4A-1 |
| Isotype | Rat IgG1 |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage and Handling | The antibody solution should be stored between 2°C and 8°C |
| Recommended Usage | For flow cytometric staining, it is recommended to use less than 0.25 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application |
B-lymphocyte antigen CD20 or CD20 is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. expressed in B-cell lymphomas, hairy cell leukemia, and B-cell chronic lymphocytic leukemia. The protein has no known natural ligand[9] and its function is to enable optimal B-cell immune response, specifically against T-independent antigens.[10] It is suspected that it acts as a calcium channel in the cell membrane. CD20 has been linked to the signaling propensity of B-cell receptor (BCR).
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