| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 110001 | 100 ug | $120 |
| Clone | HI29 |
|---|---|
| Application | FC |
| Reactivity | Human |
| Format | Purified |
| Target Name | CD53, OX44 |
| Isotype | Mouse IgG1 |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage&Handling | The antibody solution should be stored between 2°C and 8°C |
| Recommended Usage | For flow cytometric staining, it is recommended to use less than 0.25 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application |
CD53 is a 35–42 kDa type III transmembrane glycoprotein and a member of the tetraspanin family. Highly glycosylated, its apparent molecular weight decreases by ~25 kDa upon endoglycosidase F treatment. CD53 acts as a membrane organizer, forming complexes with other surface proteins to regulate signal transduction, immune cell activation, migration, and survival.
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