| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 106801 | 100 ug | $90 | ||
| 106802 | 500 ug | $210 |
| Clone | p282 (H19) |
|---|---|
| Application | FC |
| Reactivity | Human |
| Format | Purified |
| Target Name | CD59, Protectin, MIRL, H19, MACIF |
| Isotype | Mouse IgG2a |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage&Handling | The antibody solution should be stored between 2°C and 8°C |
| Recommended Usage | For flow cytometric staining, it is recommended to use less than 0.2 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application |
CD59 (Protectin) is a 19–25 kDa GPI-anchored glycoprotein expressed on hematopoietic and non-hematopoietic cells. It functions as a complement regulatory protein by binding C8/C9 and inhibiting membrane attack complex (MAC) formation, thereby protecting host cells from complement-mediated lysis. CD59 also participates in T-cell activation and costimulation. CD59 deficiency can cause hemolytic anemia, thrombosis, and cerebral infarction.
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