| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 201601 | 100 ug | $55 | ||
| 201602 | 500 ug | $110 |
| Clone | N418 |
|---|---|
| Application | FC |
| Reactivity | Mouse |
| Format | Purified |
| Target Name | CD11c, integrin αX chain, CR4, ITGAX, p150 |
| Isotype | Armenian Hamster IgG |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage and Handling | The antibody solution should be stored between 2°C and 8°C |
CD11c (Integrin αX, CR4, p150) is a ~150 kDa type I transmembrane glycoprotein that pairs non-covalently with β2 integrin (CD18) to form the αXβ2 heterodimer. It is expressed mainly on dendritic cells, with additional expression on NK cells, subsets of intestinal intraepithelial lymphocytes, monocytes/macrophages, granulocytes, and some activated T and B cells. CD11c/CD18 binds iC3b, fibrinogen, and CD54 (ICAM-1), mediating cell–cell adhesion, phagocytosis of opsonized particles, and immune cell trafficking.
Armenian Hamster IgG Isotype Ctrl
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