| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 200401 | 100 ug | $50 | ||
| 200402 | 500 ug | $110 |
| Clone | H57-597-M2a |
|---|---|
| Application | FC |
| Reactivity | Mouse |
| Format | Purified |
| Target Name | TCR β chain, TCR-β |
| Isotype | Mouse IgG2a |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage and Handling | Store the antibody undiluted at 2°C to 8°C. |
The T cell receptor (TCR) is a heterodimeric molecule expressed on the surface of T lymphocytes, responsible for recognizing antigens presented by MHC molecules. In ~95% of T cells, the TCR consists of an α (alpha) and β (beta) chain (αβ TCR), while in ~5% of T cells, it is composed of γ (gamma) and δ (delta) chains (γδ TCR). TCR β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex, which includes CD3 subunits essential for signal transduction. This complex mediates antigen recognition, signal transduction, and subsequent T cell activation.
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