| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 200311 | 25 ug | $70 | ||
| 200312 | 100 ug | $160 |
| Clone | M1/42 |
|---|---|
| Application | FC |
| Reactivity | Mouse |
| Format | Biotin |
| Target Name | H-2, major histocompatibility complex (MHC) H-2 |
| Isotype | Rat IgG2a |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | 0.5 mg/mL |
| Storage and Handling | The antibody solution should be stored between 2°C and 8°C |
| Recommended Usage | For flow cytometric staining, it is recommended to use less than 0.1 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
Mouse H-2 Complex is the murine equivalent of the human Major Histocompatibility Complex (MHC), located on chromosome 17. It encodes molecules essential for antigen presentation and immune regulation and is divided into: Class I – expressed on all nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes; presents endogenous peptides to CD8⁺ T cells via the CD3/TCR complex, aiding cytotoxic immune responses; Class II – expressed mainly on antigen-presenting cells; presents exogenous peptides to CD4⁺ T cells; Class III – encodes immune-related proteins such as complement components and cytokines.
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