| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 201511 | 25 tests | $55 | ||
| 201512 | 100 tests | $110 |
| Clone | 6D5 |
|---|---|
| Application | FC |
| Reactivity | Mouse |
| Format | FITC |
| Target Name | CD19, B4, CVID3, Leu-12, MGC12802 |
| Isotype | Rat IgG2a |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | Supplied at a lot-specific concentration. |
| Storage and Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Recommended Usage | For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
| Excitation Laser | Blue Laser (488 nm) |
CD19, also known as B-lymphocyte antigen CD19, B4, Leu-12, or CVID3, is a type I transmembrane glycoprotein encoded by the CD19 gene. It is expressed throughout B cell development from the pro-B stage to mature B cells and is present on most B lineage cells. CD19 functions as an adaptor protein, recruiting cytoplasmic signaling molecules to the membrane, and forms part of the CD19/CD21/CD81 complex, which lowers the activation threshold for B cell receptor (BCR) signaling. Because of its consistent expression on B cells, CD19 serves as a key biomarker for B cell development and is widely used in the diagnosis of B cell lymphomas and leukemias. It is also a major therapeutic target in immunotherapies, including CAR T-cell therapy for B cell malignancies.
FITC Rat IgG2a Isotype control
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