| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 303101 | 25 ug | $80 | ||
| 303102 | 100 ug | $220 |
| Clone | 1016AH4M2 |
|---|---|
| Application | FC |
| Reactivity | N/A |
| Format | Purified |
| Target Name | Human IgG4 isotype control |
| Isotype | Human IgG4 |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage&Handling | Quick spin the vial after receiving. The antibody solution should be stored between 2°C and 8°C without dilution. |
| Recommended Usage | Use at concentrations comparable to those used for the target-specific antibody |
There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). The measurement of immunoglobulin G can be a diagnostic tool for certain conditions. This clone carries the S228P mutation, which helps reduce half-antibody formation commonly seen in the IgG4 subclass. It also includes the L235E mutation, which minimizes unwanted side effects by silencing Fc-mediated immune responses.
Human IgG4 isotype control (S228P, L235E) TDS
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