iF647 Anti-Human CD59

Product Details


Clonep282 (H19)
ApplicationFC
ReactivityHuman
FormatiF647
Target NameCD59, Protectin, MIRL, H19, MACIF
IsotypeMouse IgG2a
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein ConcentrationSupplied at a lot-specific concentration.
Storage&HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended UsageFor flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application.
Excitation LaserRed Laser (633 nm)

Background Information


CD59 (Protectin) is a 19–25 kDa GPI-anchored glycoprotein expressed on hematopoietic and non-hematopoietic cells. It functions as a complement regulatory protein by binding C8/C9 and inhibiting membrane attack complex (MAC) formation, thereby protecting host cells from complement-mediated lysis. CD59 also participates in T-cell activation and costimulation. CD59 deficiency can cause hemolytic anemia, thrombosis, and cerebral infarction.

Data Sheets


iF647 Anti-Human CD59 TDS

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iF647 Mouse IgG2a Isotype Control


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