| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 800501 | 25 ug | $245 | ||
| 800502 | 100 ug | $595 |
| Application | FC |
|---|---|
| Format | Liquid, PE |
| Expression Host | CHO |
| Target Name | CD64, FCGR1A, FCG1, FCGR1, IGFR1 |
| Species | Human |
| Sources | Recombinant human CD64 (Gln16–Thr287) with a C-terminal His tag is expressed in CHO cells and conjugated to PE. |
| Accession Number | P12314 |
| Molecular Weight | The protein has a predicted molecular weight of 32kDa. Under DTT-reducing conditions, it migrates at approximately 50–60 kDa on SDS-PAGE prior to conjugation. |
| Affinity Tag | C-His |
| Regulatory Status | RUO |
| Formulation | 1xPBS buffer, pH7.4, 0.09% NaN3 with a carrier protein |
| Endotoxin level | Not tested |
| Protein Concentration | 25µg size is bottled at 0.1mg/mL concentration. 100 µg size is bottled at lot specific concentration. |
| Storage and Handling | Briefly centrifuge the vial upon receipt. An unopened vial may be stored at 2–8°C for up to six months. |
CD64, also known as FcγRI or FcR I, is a 72 kDa type I glycoprotein and a member of the immunoglobulin superfamily. This high-affinity IgG Fc receptor is predominantly expressed on monocytes, macrophages, dendritic cells, and activated granulocytes. Its expression can be upregulated by IFN-γ stimulation, enhancing its role in immune responses. CD64 binds IgG immune complexes and is involved in several crucial immune functions, including antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC). By mediating these processes, CD64 contributes to the activation of innate immune responses and the clearance of immune complexes.
PE Conjugated Human CD64 Protein (C-His) TDS
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