iF488 Anti-human/mouse/rat CD278 (ICOS) Antibody

Product Details


CloneC398.4A
ApplicationFlow Cytometry
ReactivityHuman, mouse, rat
FormatiF488
Target NameCD278, ICOS, Inducible Costimulatory molecule
IsotypeArmenian Hamster IgG
Antibody TypeMonoclonal
Regulatory StatusRUO
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
Protein ConcentrationSupplied at a lot-specific concentration.
Storage&HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended UsageFor flow cytometric staining, it is recommended to use 5 µL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. iF488 has an excitation max at 491 nm and an emission max at 516 nm.
Excitation LaserBlue Laser (488 nm)
See All FormatsClone C398.4A

Background Information


ICOS is a 47–57 kDa costimulatory molecule homologous to CD28/CTLA-4 and is expressed on activated T cells and a subset of thymocytes. Engagement of ICOS enhances T cell proliferation, promotes cytokine production such as IL-4 and IL-10, and plays an important role in humoral immunity and Th2 cell differentiation.

Isotype Control


iF488 Armenian Hamster IgG Isotype Control Antibody

Data Sheets


iF488 Anti-human/mouse/rat CD278 (ICOS) Antibody TDS

Related Protocols


Flow Cytometry Protocol


Have a product or application question? Consult our FAQs or contact us.